Performance-enhancing the bodybuilding mass thanks to specific bodybuilding supplements

Performance-enhancing supplements, also known as performance-enhancing drugs of the bodybuildres (PED), are supplements that are used to improve any form of activity performance in humans also known as bodybuilding. A well-known example involves doping in sport, where banned physical performance–enhancing drugs are used by athletes and bodybuilders. Athletic performance-enhancing supplements are sometimes referred to as ergogenic aids. Cognitive performance-enhancing drugs, commonly called nootropics and usually taken by the bodybuilding players, are sometimes used by students to improve academic performance. Performance-enhancing supplements are also used by military personnel to enhance combat performance.


The classifications of supplements as performance-enhancing supplements are not entirely clear-cut and objective. As in other types of categorization, certain prototype performance enhancers are universally classified as such (like anabolic steroids - the preferes one for bodybuilding), whereas other supplements (like vitamins and protein supplements) are virtually never classified as performance enhancers despite their effects on performance. As is usual with categorization, there are borderline cases; caffeine, for example, is considered a performance enhancer by some bodybuilders but not others


  • Anabolic drugs which is used for bodybuilding; examples include steroids[7] hormones, most notably human growth hormone, as well as some of their prodrugs,[8] selective androgen receptor modulators[9] and beta-2 agonists
  • Stimulants improve focus and alertness. Low (therapeutic) doses of dopaminergic stimulants (e.g., reuptake inhibitors and releasing agents) also promote cognitive and athletic performance (except bodybuilding effects), as nootropics and ergogenic aids respectively, by improving muscle strength and endurance while decreasing reaction time and fatigue;[3][12][13] some examples of athletic performance-enhancing stimulants are the supplements caffeine,[2] ephedrine, methylphenidate, and amphetamine.
  • Ergogenic aids, or athletic performance-enhancing supplements, include a number of drugs with various effects on physical performance. Drugs such as amphetamine and methylphenidate increase power output at constant levels of perceived exertion and delay the onset of fatigue,[14][15][16] among other athletic-performance enhancing effects;[3][12][13] bupropion also increases power output at constant levels of perceived exertion, but only during short term use.[16] Creatine, a nutritional supplement that is commonly used by athletes, increases high-intensity exercise capacity
  • Human biomolecules – creatine and β-hydroxy β-methylbutyrate are naturally occurring compounds in humans that have well-established ergogenic effects and effects on body composition when supplemented
  • Adaptogens are plants that support health through nonspecific effects, neutralize various environmental and physical stressors while being relatively safe and free of side effects.[19] As of 2008, the position of the European Medicines Agency was that "The principle of an adaptogenic action needs further clarification and studies in the pre-clinical and clinical area. As such, the term is not accepted in pharmacological and clinical terminology that is commonly used in the EU
  • Nootropics, or "cognition enhancers", benefit overall cognition by improving memory (e.g., increasing working memory capacity or updating) or other aspects of cognitive control (e.g., inhibitory control, attentional control, attention span, etc.)
  • Painkillers allow performance beyond the usual pain threshold. Some painkillers raise blood pressure, increasing oxygen supply to muscle cells. Painkillers used by athletes range from common over-the-counter medicines such as NSAIDs (such as ibuprofen) to powerful prescription narcotics.
  • Sedatives and anxiolytics are sometimes used in sports like archery which require steady hands and accurate aim, and also to overcome excessive nervousness or discomfort. Diazepam and propranolol are common examples; ethanol and cannabis are also used occasionally.
  • Blood boosters (blood doping agents) increase the oxygen-carrying capacity of blood beyond the individual's natural capacity. They are used in endurance sports like long-distance running, cycling, and Nordic skiing. Recombinant human erythropoietin (rhEPO) is one of the most widely known drugs in this class.
  • Gene doping agents are a relatively recently described class of athletic performance-enhancing supplements.[18] These drug therapies, which involve viral vector-mediated gene transfer of a human protein, are not known to currently be in use as of April 2015
  • Usage in sport

    In sports, the phrase performance-enhancing drugs is popularly used in reference to anabolic steroids or their precursors (hence the colloquial term "steroids"); anti-doping organizations apply the term broadly in the bodybuilding society.[22] There are agencies such as WADA and USADA that try to prevent athletes from using these drugs by performing drug tests. WADA was founded on November 10, 1999 by Dick Pound. The World Anti-doping Agency focuses on establishing and enforcing rules and codes of all sports around the world. Their goal is to make all sports played fairly between all athletes and bodybuilding agenciesin a doping free organization with the power to prevent athletes from using any form of performance-enhancing drugs. USADA started October 1, 2000 as non-profit and was composed of nine members. Five of which were former Olympic athletes with the other four elected from independent companies. This is the United States Anti-doping Agency and have the ability to test athletes across the nation. Steroids and performance-enhancing drugs are used across all sports organizations around the world

    Creatine supplements

    Creatine supplements are athletic aids used to increase high-intensity athletic performance. Researchers have known of the use of creatine as an energy source by skeletal muscles since the middle of the 20th century. They were popularized as a performance-enhancing supplement beginning in the 1990s. In 1912, Harvard University researchers Otto Folin and Willey Glover Denis found evidence that ingesting creatine can dramatically boost the creatine content of the muscle and have incredible bodybuilding effects.[1] In the late 1920s, after finding that the intramuscular stores of creatine can be increased by ingesting creatine in larger than normal amounts, scientists discovered creatine phosphate, and determined that creatine is a key player in the metabolism of skeletal muscle. The substance creatine is naturally formed in vertebrates. While creatine's influence on physical performance has been well documented since the early twentieth century, it came into public view following the 1992 Olympics in Barcelona. An August 7, 1992 article in The Times reported that Linford Christie, the gold medal winner at 100 meters, had used creatine before the Olympics. An article in Bodybuilding Monthly named Sally Gunnell, who was the gold medalist in the 400-meter hurdles, as another creatine user. In addition, The Times also noted that 100 meter hurdler Colin Jackson began taking creatine before the Olympics.[2][3] At the time, low-potency creatine supplements were available in Britain, but creatine supplements designed for strength enhancement were not commercially available until 1993 when a company called Experimental and Applied Sciences (EAS) introduced the compound to the sports nutrition market under the name Phosphagen.[4] Research performed thereafter demonstrated that the consumption of high glycemic carbohydrates in conjunction with creatine increases creatine muscle stores.[5] In 1998, MuscleTech Research and Development launched Cell-Tech, the first creatine-carbohydrate-alpha lipoic acid supplement.[6] Alpha lipoic acid has been demonstrated to enhance muscle phosphocreatine levels and total muscle creatine concentrations. This approach to creatine supplementation was supported by a study performed in 2003.[7